Niagen IV Therapy
Advanced NAD+ support through precision IV infusion
Targeted Cellular Replenishment
Niagen IV delivers pharmaceutical-grade nicotinamide riboside chloride (NRCl), a clinically studied NAD+ precursor that supports cellular metabolism, energy production, and healthy aging. As part of our integrated aesthetic and longevity healthcare offerings, this therapy helps optimize your internal health to match your external goals.
Why Niagen IV at PFRANKMD
- Rapid NAD+ replenishment—20% increase within 3 hours
- Efficient intracellular delivery with reduced GI or immune side effects
- Shorter infusion time—typically 10 minutes to 3 hours
- Pharmaceutical-grade sourcing under FDA-compliant standards
- Part of a personalized longevity and optimization protocol
How It Works
Unlike traditional NAD+ infusions, which require long infusion times and often cause uncomfortable side effects, Niagen IV uses nicotinamide riboside chloride to bypass rate-limiting steps in NAD+ metabolism. Once infused, NRCl is efficiently absorbed and converted into NAD+ within cells, enhancing mitochondrial function and supporting systemic cellular health.
Niagen (NR) IV Drips
What is Niagen® (NR) IV Drip Therapy?
Experience the superior way to feel the effects of NAD+ therapy to help reduce age- and stress-related cellular damage and improve energy and metabolism.
Benefits of Niagen (NR) IV Drips may include:
– Improved cellular and metabolic health
– Enhanced cellular energy to combat fatigue
– Reduced oxidative stress for faster recovery
– Decreased inflammation for healthier aging
– Boosted cognitive function
The Niagen (NR) IV Drips Experience
Why is NR superior to NAD+?
When receiving NAD+ therapy, the active form of NAD+ is injected directly into your bloodstream. However, high concentrations of NAD+ are not naturally present in the body, so this may cause adverse experiences, such as headaches and nausea. Since NR is the precursor to NAD+ that is converted naturally inside cells, Niagen (NR) has been shown to provide 20% higher levels of NAD+ at the 3-hour mark compared to baseline with fewer adverse experiences.
For this medical service, please plan to arrive early to complete any necessary paperwork and participate in a Telemedicine consultation with a Nurse Practitioner. Medical paperwork needs to be completed once a year. During your Telemedicine session, you’ll have the opportunity to discuss your health history, wellness goals and any questions you may have about the treatment. A Registered Nurse will then take your vital signs before guiding you to a comfortable space for your infusion and carefully insert a small catheter into your vein. We encourage you to relax during the treatment by enjoying a book, listening to a podcast or working on your laptop.
The Niagen IV Drip Therapy experience does not require a loading dose and offers a 75% faster infusion time, compared to NAD+ IV Drip Therapy.
After the Niagen (NR) IV Drip is completed, you can enjoy a refreshing cleansing IV infusion. This drip includes essential B Vitamins and amino acids like Glutamine and Proline to support the creation of new cells, boost recovery and enhance immunity and digestion.
NR research is continually evolving, and we may adjust our options and protocols accordingly.
What to Expect
Consultation: Your provider will evaluate your overall health, goals, and baseline labs to determine if Niagen IV fits into your personal optimization protocol.
Infusion: The IV drip typically lasts about 45 minutes, depending on dose and tolerance.
Aftercare: Most patients report a subtle but steady improvement in focus, energy, and recovery within 24–72 hours.
Schedule your Niagen IV consultation to explore how targeted NAD+ replenishment can support your performance, vitality, and longevity.


