At PFRANKMD, we believe in optimizing your health from the inside out. Peptide therapy is a key component of our comprehensive approach to aesthetic and longevity medicine, supporting patients in achieving enhanced vitality, improved skin health, balanced hormones, and accelerated healing. Under the medical direction of Dr. Paul Jarrod Frank, peptide protocols are customized to each patient’s goals—whether that’s improved sleep, cognitive clarity, athletic performance, or graceful aging.
Peptide Therapy
Advancing Aesthetic and Longevity Healthcare with Peptide Therapy
What Are Peptides?
Peptides are short chains of amino acids that function as signaling molecules within the body, instructing cells to perform specific tasks. Naturally occurring peptides regulate critical biological processes including inflammation, tissue repair, metabolism, and hormone production. In peptide therapy, synthetic versions of these naturally occurring peptides are used to target and enhance those same physiological functions.
At PFRANKMD, we only utilize pharmaceutical-grade peptides sourced from trusted, accredited compounding pharmacies to ensure safety, efficacy, and consistency.
Why Peptide Therapy?
As we age, the natural production of key peptides in the body declines, contributing to fatigue, weight gain, reduced muscle tone, poor sleep, joint pain, and visible signs of aging. Peptide therapy addresses this decline by:
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Stimulating collagen production for firmer, more youthful skin
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Enhancing fat metabolism and muscle development
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Improving cognitive focus and memory
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Supporting hormone balance and libido
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Accelerating healing post-injury or procedure
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Promoting deeper, more restorative sleep
Targeted Peptides Available at PFRANKMD
Each peptide is selected based on your wellness goals. Some of the most utilized options in our aesthetic and longevity practice include:
Peptide Therapy for Muscle Growth, Athletic Performance & Recovery
CJC-1295: Promotes natural growth hormone release for fat loss and muscle gain.
Ipamorelin: Enhances recovery and supports lean muscle development.
BPC-157: Speeds healing and reduces inflammation in muscles and joints.
Sermorelin: Boosts natural HGH production with minimal side effects.
Peptide Therapy for Healthy Aging & Skin Repair
GHK-Cu: Improves skin elasticity, firmness, and wound healing.
Thymosin Alpha-1: Supports immune health and inflammation control.
Your expert provider will consider each of your aesthetic and longevity healthcare goals when designing your peptide protocol.
Peptide Therapy Delivery Methods
Peptides at PFRANKMD can be administered in several forms depending on patient preference and clinical goals:
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Subcutaneous injection
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Transdermal cream
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Nasal spray
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Oral tablets or capsules
Who Is a Candidate for Peptide Therapy?
Anyone looking to optimize their health, improve recovery, support graceful aging, or elevate energy and cognitive function may benefit from peptide therapy. Patients dealing with chronic fatigue, hormonal imbalance, post-COVID symptoms, perimenopause/menopause, and aesthetic skin concerns often experience meaningful improvements.
All treatment plans are designed following a comprehensive consultation to evaluate your medical history, lab results, and long-term goals.
Schedule a Consultation
Peptides are a powerful, scientifically backed tool in the evolving world of aesthetic and longevity healthcare. At PFRANKMD, we’re here to guide you through the latest innovations in regenerative medicine, always with your safety, results, and optimization in mind. Schedule your personalized consultation and discover how peptide therapy can help you feel and look your best.
SOCIAL MEDIA
𝐂𝐎𝟐 𝐋𝐚𝐬𝐞𝐫 𝐯𝐬 𝐌𝐢𝐫𝐢𝐚: 𝐔𝐧𝐝𝐞𝐫𝐬𝐭𝐚𝐧𝐝𝐢𝐧𝐠 𝐀𝐜𝐧𝐞 𝐒𝐜𝐚𝐫 𝐎𝐩𝐭𝐢𝐨𝐧𝐬
@dr.connieyang breaks down two of our most effective options for acne scarring. The CO2 laser is the gold standard for deeper collagen remodeling and more dramatic textural improvement, though it comes with a longer recovery. Miria is a novel non-ablative laser that offers controlled resurfacing with less aggressiveness and shorter downtime.
Both options can be transformative when used thoughtfully and in expert hands. At PFRANKMD, our goal is always to match the right device to the right patient for the safest, most effective pro-aging outcome.
𝐓𝐚𝐩 𝐭𝐡𝐞 𝐥𝐢𝐧𝐤 𝐢𝐧 𝐛𝐢𝐨 𝐨𝐫 𝐜𝐚𝐥𝐥 (212) 327-2919 to schedule a consultation.
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐂𝐎𝟐 𝐋𝐚𝐬𝐞𝐫 𝐟𝐨𝐫 𝐅𝐢𝐧𝐞 𝐋𝐢𝐧𝐞𝐬 𝐚𝐧𝐝 𝐖𝐫𝐢𝐧𝐤𝐥𝐞𝐬 𝐀𝐫𝐨𝐮𝐧𝐝 𝐭𝐡𝐞 𝐌𝐨𝐮𝐭𝐡
The mouth is one of the first areas to show visible aging. Years of sun exposure, collagen loss, and constant muscle movement make this region especially prone to fine lines and deeper etched-in wrinkles that topicals cannot correct. This is where advanced CO2 resurfacing remains the gold standard of lasers for true skin rejuvenation.
CO2 can treat the delicate crepey skin around the mouth that even a facelift cannot improve. It works by tightening, smoothing, and rebuilding the skin from the inside out through powerful collagen and elastin stimulation. Even one treatment can dramatically refine texture, soften wrinkles, and restore a firmer, more youthful appearance.
At PFRANKMD, we use precision-based energy settings to resurface the area safely and effectively with measurable, long-term results. Skin continues to improve for months as new collagen forms.
Click the link in bio or call (212) 327-2919 to schedule a consultation and elevate your long-term skin health.
𝐔𝐥𝐭𝐡𝐞𝐫𝐚𝐩𝐲 𝐏𝐫𝐢𝐦𝐞 𝐟𝐨𝐫 𝐋𝐨𝐰𝐞𝐫 𝐅𝐚𝐜𝐞 𝐚𝐧𝐝 𝐉𝐨𝐰𝐥 𝐓𝐢𝐠𝐡𝐭𝐞𝐧𝐢𝐧𝐠
This patient presented with concerns about early laxity along the lower face and jowl area. Ultherapy Prime was used to deliver precise, targeted tightening to the deeper structural layers that define the lower face. The results shown here are four months after treatment, during the peak window of collagen remodeling.
Ultherapy works by delivering micro-focused ultrasound energy to the foundational tissues that support lift and contour. This stimulates new collagen, creating gradual tightening and improved definition. Patients often begin noticing changes around the four-week mark, with full results developing between three and six months.
Ultherapy is an excellent option for patients looking for visible lift, enhanced jawline contour, and tightening without surgery or downtime.
Treatment performed by Registered Nurse Jennifer Schroder @bomb.ass.skin
𝐒𝐭𝐫𝐞𝐭𝐜𝐡 𝐌𝐚𝐫𝐤 𝐓𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭: 𝐑𝐞𝐝𝐧𝐞𝐬𝐬 𝐚𝐧𝐝 𝐒𝐤𝐢𝐧 𝐐𝐮𝐚𝐥𝐢𝐭𝐲
Stretch marks form when skin’s elastic fibers are stretched beyond their capacity to repair, often from pregnancy, growth spurts, weight changes, or hormonal shifts.
This patient began treatment while her stretch marks were still red, which is the most responsive stage for improvement. In the photos, you can see a clear reduction in redness, a smoother texture across the abdomen, and softer edges where the stretch marks once appeared deeper and more inflamed.
Treatment began with Vbeam to calm the redness and vascular activity. Pico was then added to break up pigment and stimulate collagen remodeling. Customized topicals between sessions supported ongoing healing and improved overall skin quality.
Her texture, color, and uniformity have improved significantly. Most patients require 6 to 10 treatments for visible fading, depending on the age, depth, and type of stretch marks. If you prolong treatment, the stretch marks will most likely be permanent and significantly harder to treat.
Every body is different, which is why PFRANKMD uses advanced, customized treatment plans to achieve the best possible outcome.
✨ Treatment performed by Registered Nurse Jennifer Schroder @bomb.ass.skin
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐌𝐢𝐫𝐢𝐚: 𝐀𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐍𝐨𝐧 𝐀𝐛𝐥𝐚𝐭𝐢𝐯𝐞 𝐒𝐤𝐢𝐧 𝐑𝐞𝐣𝐮𝐯𝐞𝐧𝐚𝐭𝐢𝐨𝐧
Miria is a non invasive treatment that reduces fine lines, softens wrinkles, improves crepey skin, and enhances overall texture with minimal downtime. The device delivers cone shaped heat deep into the dermis to stimulate collagen, tighten skin, and support long term maintenance for patients who want smoother, firmer, more youthful looking skin without the recovery of ablative lasers.
Watch the video to see how this technology penetrates deeply, creates controlled heat, and rejuvenates the skin while keeping recovery minimal and treatment tolerable.
Click the link in bio to learn if this treatment is right for you.
𝐈𝐧 𝐂𝐚𝐬𝐞 𝐘𝐨𝐮 𝐌𝐢𝐬𝐬𝐞𝐝 𝐓𝐡𝐞 𝐃𝐞𝐫𝐦 𝐂𝐨𝐮𝐜𝐡: 𝐓𝐡𝐞 𝐀𝐫𝐭 𝐨𝐟 𝐑𝐞𝐜𝐨𝐯𝐞𝐫𝐲
On this derm couch, we dive into the art of post-treatment healing—keeping it simple from skin to surgery. From minimal skincare and internal wellness to the benefits of peptides, we explore why less really is more when it comes to recovery.
Watch for more insights on how to support your body and skin from the inside out for optimal healing and lasting results.
𝐀𝐜𝐡𝐢𝐞𝐯𝐞 𝐓𝐢𝐠𝐡𝐭𝐞𝐫, 𝐒𝐦𝐨𝐨𝐭𝐡𝐞𝐫 𝐒𝐤𝐢𝐧 𝐰𝐢𝐭𝐡 𝐌𝐢𝐫𝐢𝐚 𝐒𝐤𝐢𝐧 𝐓𝐢𝐠𝐡𝐭𝐞𝐧𝐢𝐧𝐠
Miria Skin Tightening is designed to target superficial skin concerns, enhancing elasticity, reducing fine lines, and improving the appearance of acne scars for a refreshed, youthful look.
This advanced treatment uses innovative energy-based technology to stimulate collagen production, delivering natural, long-lasting results with minimal downtime.
Whether you’re looking to firm the face, neck, or body, or improve skin texture and acne scars, Miria offers a customized solution tailored to your skin’s unique needs. Say goodbye to superficial skin concerns and hello to rejuvenation!
✨Call (212) 327-2919 or click the link in bio to schedule your consultation.
𝐑𝐞𝐩𝐚𝐢𝐫. 𝐑𝐞𝐣𝐮𝐯𝐞𝐧𝐚𝐭𝐞. 𝐑𝐞𝐯𝐞𝐚𝐥.
As the seasons change, so does your skin, and fall is the ideal time to restore, resurface, and renew.
At 𝗣𝗙𝗥𝗔𝗡𝗞𝗠𝗗, we offer a full spectrum of advanced skin rejuvenation treatments to repair summer damage and reveal smoother, firmer, healthier skin:
𝗙𝗿𝗮𝘅𝗲𝗹 – A fractional laser that targets pigment, texture, and fine lines, stimulating collagen for brighter, tighter skin.
𝗠𝗶𝗿𝗶𝗮 – A next-generation non-ablative laser that tightens skin and smooths wrinkles with minimal downtime.
𝗘𝗹𝗹𝗮𝗰𝗼𝗿 – The first device to physically remove micro-portions of skin, lifting and tightening without surgery or visible scarring.
Each technology is customized for your skin type, lifestyle, and goals — helping you achieve a refreshed, naturally radiant result that lasts.
𝗦𝗰𝗵𝗲𝗱𝘂𝗹𝗲 𝗮 𝗰𝗼𝗻𝘀𝘂𝗹𝘁𝗮𝘁𝗶𝗼𝗻 𝗮𝘁 𝗣𝗙𝗥𝗔𝗡𝗞𝗠𝗗 to learn which treatment is right for you.
📍 Upper East Side & West Village | 💻 Link in bio
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐄𝐥𝐥𝐚𝐜𝐨𝐫 𝐌𝐢𝐜𝐫𝐨𝐜𝐨𝐫𝐢𝐧𝐠 𝟏𝟎𝟏: 𝐇𝐨𝐰 𝐃𝐨𝐞𝐬 𝐓𝐡𝐢𝐬 𝐒𝐤𝐢𝐧 𝐑𝐞𝐦𝐨𝐯𝐚𝐥 𝐓𝐞𝐜𝐡𝐧𝐢𝐪𝐮𝐞 𝐖𝐨𝐫𝐤?
Ellacor uses fractional microcoring technology, a first-of-its-kind, minimally invasive treatment that physically removes tiny micro-cores of skin to improve texture, firmness, and tightness. By precisely extracting thousands of microscopic skin columns, the surrounding tissue contracts and heals naturally, creating a smoother, tighter appearance without surgery or visible scarring.
Unlike traditional energy-based microneedling, Ellacor does not use heat, radiofrequency, or laser energy to stimulate collagen. Instead, it achieves actual skin removal and tightening through mechanical precision, reducing laxity and fine lines more effectively and with less downtime.
This scarless skin removal technology can be used on multiple body areas, including the face, neck, and décolletage, offering patients a powerful alternative to more invasive procedures as the demand for natural-looking, nonsurgical rejuvenation continues to grow.
To learn more, click the link in bio and call our office to schedule a consultation.
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐒𝐭𝐫𝐞𝐭𝐜𝐡 𝐌𝐚𝐫𝐤𝐬 & 𝐒𝐤𝐢𝐧 𝐋𝐚𝐱𝐢𝐭𝐲: 𝐕𝐛𝐞𝐚𝐦 + 𝐌𝐢𝐫𝐢𝐚
Stretch marks and skin laxity often develop as a result of pregnancy, weight fluctuations, or the natural aging process. At PFRANKMD, we combine the Vbeam laser and Miria laser to effectively address both concerns.
Miria uses advanced non-ablative laser technology to heat the deeper layers of the skin, improving elasticity and firmness by stimulating new collagen and elastin production.
Vbeam targets redness and discoloration in stretch marks by reducing vascular inflammation and stimulating collagen remodeling for a more even skin tone.
Together, these treatments work synergistically to reduce the appearance of stretch marks and restore smoother, tighter, and more youthful-looking skin with minimal downtime.
To learn more or schedule a consultation, call (212) 327-2919 or click the link in bio.
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐒𝐊𝐈𝐍 𝐑𝐄𝐉𝐔𝐕𝐄𝐍𝐀𝐓𝐈𝐎𝐍 𝐅𝐎𝐑 𝐓𝐇𝐄 𝐂𝐇𝐀𝐍𝐆𝐈𝐍𝐆 𝐒𝐄𝐀𝐒𝐎𝐍𝐒
As the weather cools, 𝐨𝐮𝐫 𝐥𝐚𝐬𝐞𝐫𝐬 𝐚𝐫𝐞 𝐡𝐞𝐚𝐭𝐢𝐧𝐠 𝐮𝐩. Fall is the ideal time for skin rejuvenation, since you are less likely to get intense sun exposure while your skin is in its healing phase. 𝐃𝐨𝐰𝐧𝐭𝐢𝐦𝐞 𝐚𝐥𝐬𝐨 𝐟𝐞𝐞𝐥𝐬 𝐞𝐚𝐬𝐢𝐞𝐫 𝐭𝐨 𝐦𝐚𝐧𝐚𝐠𝐞, making this the perfect moment to commit to treatments that deliver real results.
At PFRANKMD, 𝐰𝐞 𝐨𝐟𝐟𝐞𝐫 𝐚 𝐬𝐩𝐞𝐜𝐭𝐫𝐮𝐦 𝐨𝐟 𝐫𝐞𝐬𝐮𝐫𝐟𝐚𝐜𝐢𝐧𝐠 𝐚𝐧𝐝 𝐭𝐢𝐠𝐡𝐭𝐞𝐧𝐢𝐧𝐠 𝐭𝐞𝐜𝐡𝐧𝐢𝐪𝐮𝐞𝐬 that target different layers of the skin to improve sun damage, texture, tone, and overall elasticity. 𝐅𝐫𝐚𝐱𝐞𝐥 is a true workhorse for refining tone, fading scars, shrinking pores, and plumping skin. 𝐌𝐢𝐫𝐢𝐚 delivers advanced resurfacing for pigmentation and fine lines, while 𝐄𝐥𝐥𝐚𝐜𝐨𝐫 fractional micro-coring provides powerful tightening and rejuvenation without scarring.
𝐓𝐡𝐢𝐧𝐤 𝐨𝐟 𝐭𝐡𝐞𝐬𝐞 𝐭𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭𝐬 𝐚𝐬 𝐲𝐨𝐮𝐫 𝐬𝐞𝐚𝐬𝐨𝐧𝐚𝐥 𝐫𝐞𝐬𝐞𝐭: repairing summer’s damage, renewing collagen production, and revealing fresh, healthy skin that will carry you through the holidays and into the new year.
📞 𝐂𝐚𝐥𝐥 (212) 327-2919 𝐨𝐫 𝐜𝐥𝐢𝐜𝐤 𝐭𝐡𝐞 𝐥𝐢𝐧𝐤 𝐢𝐧 𝐛𝐢𝐨 𝐭𝐨 𝐬𝐜𝐡𝐞𝐝𝐮𝐥𝐞 𝐲𝐨𝐮𝐫 𝐜𝐨𝐧𝐬𝐮𝐥𝐭𝐚𝐭𝐢𝐨𝐧.
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐄𝐥𝐥𝐚𝐜𝐨𝐫 𝐓𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 𝐏𝐨𝐬𝐭-𝐎𝐩 𝐃𝐚𝐲 𝟏: 𝐐𝐮𝐢𝐜𝐤 𝐇𝐞𝐚𝐥𝐢𝐧𝐠, 𝐍𝐨 𝐏𝐚𝐢𝐧
We are with our patient here one day after her Ellacor micro-coring treatment for facial rejuvenation. She experienced no pain during or after the procedure, with only mild swelling visible in the treated areas. Already, most of the tiny treatment sites have closed, leaving behind subtle pinpoint marks as her skin continues to heal.
With the latest Ellacor device, recovery is faster and more comfortable than ever. Patients can return to their normal routines right away, while avoiding sun exposure for two weeks to protect the skin and prevent pigmentation changes.
Results build gradually over the next 1–6 weeks as collagen remodeling takes place—making Ellacor an ideal pre-event treatment (this patient is preparing for a wedding in January).
Ellacor is the perfect gap procedure for those looking for skin tightening and rejuvenation, without surgery or scars.
📞 Call (212) 327-2919 or click the link in bio to schedule a consultation.
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
Frequently Asked Questions: Peptide Therapy at PFRANKMD
What are peptides and how do they work?
Peptides are small chains of amino acids that act as messengers in the body, instructing cells to carry out specific functions like healing, repair, or hormone release.
Are peptides safe?
Yes. When prescribed and administered under medical supervision using pharmacy-grade sources, peptides are generally well-tolerated and have low risk of adverse effects.
How long does it take to see results from peptide therapy?
Most patients begin noticing changes within a few weeks. Full benefits are typically experienced after 8–12 weeks of consistent use.
Can peptides help with weight loss?
Yes. Certain peptides such as CJC-1295, Tesamorelin, and GLP-1 analogs can support fat loss, improve metabolism, and regulate appetite.
Do I need lab work before starting peptide therapy?
Yes. A full health evaluation, including lab testing, helps ensure your treatment plan is safe, targeted, and effective.
Is peptide therapy only for older adults?
No. Peptide therapy can benefit adults of any age who are seeking to enhance their wellness, athletic performance, skin health, or recovery.
How is peptide therapy different at PFRANKMD?
Our approach is precision-based, backed by the latest longevity research, and delivered under the guidance of leading medical experts in the field of aesthetic and functional wellness.