At PFRANKMD, we believe in optimizing your health from the inside out. Peptide therapy is a key component of our comprehensive approach to aesthetic and longevity medicine, supporting patients in achieving enhanced vitality, improved skin health, balanced hormones, and accelerated healing. Under the medical direction of Dr. Paul Jarrod Frank, peptide protocols are customized to each patient’s goals—whether that’s improved sleep, cognitive clarity, athletic performance, or graceful aging.
Peptide Therapy
Advancing Aesthetic and Longevity Healthcare with Peptide Therapy
What Are Peptides?
Peptides are short chains of amino acids that function as signaling molecules within the body, instructing cells to perform specific tasks. Naturally occurring peptides regulate critical biological processes including inflammation, tissue repair, metabolism, and hormone production. In peptide therapy, synthetic versions of these naturally occurring peptides are used to target and enhance those same physiological functions.
At PFRANKMD, we only utilize pharmaceutical-grade peptides sourced from trusted, accredited compounding pharmacies to ensure safety, efficacy, and consistency.
Why Peptide Therapy?
As we age, the natural production of key peptides in the body declines, contributing to fatigue, weight gain, reduced muscle tone, poor sleep, joint pain, and visible signs of aging. Peptide therapy addresses this decline by:
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Stimulating collagen production for firmer, more youthful skin
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Enhancing fat metabolism and muscle development
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Improving cognitive focus and memory
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Supporting hormone balance and libido
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Accelerating healing post-injury or procedure
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Promoting deeper, more restorative sleep
Targeted Peptides Available at PFRANKMD
Each peptide is selected based on your wellness goals. Some of the most utilized options in our aesthetic and longevity practice include:
Peptide Therapy for Muscle Growth, Athletic Performance & Recovery
CJC-1295: Promotes natural growth hormone release for fat loss and muscle gain.
Ipamorelin: Enhances recovery and supports lean muscle development.
BPC-157: Speeds healing and reduces inflammation in muscles and joints.
Sermorelin: Boosts natural HGH production with minimal side effects.
Peptide Therapy for Healthy Aging & Skin Repair
GHK-Cu: Improves skin elasticity, firmness, and wound healing.
Thymosin Alpha-1: Supports immune health and inflammation control.
Your expert provider will consider each of your aesthetic and longevity healthcare goals when designing your peptide protocol.
Peptide Therapy Delivery Methods
Peptides at PFRANKMD can be administered in several forms depending on patient preference and clinical goals:
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Subcutaneous injection
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Transdermal cream
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Nasal spray
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Oral tablets or capsules
Who Is a Candidate for Peptide Therapy?
Anyone looking to optimize their health, improve recovery, support graceful aging, or elevate energy and cognitive function may benefit from peptide therapy. Patients dealing with chronic fatigue, hormonal imbalance, post-COVID symptoms, perimenopause/menopause, and aesthetic skin concerns often experience meaningful improvements.
All treatment plans are designed following a comprehensive consultation to evaluate your medical history, lab results, and long-term goals.
Schedule a Consultation
Peptides are a powerful, scientifically backed tool in the evolving world of aesthetic and longevity healthcare. At PFRANKMD, we’re here to guide you through the latest innovations in regenerative medicine, always with your safety, results, and optimization in mind. Schedule your personalized consultation and discover how peptide therapy can help you feel and look your best.
SOCIAL MEDIA
𝐏𝐞𝐩𝐭𝐢𝐝𝐞𝐬 𝐚𝐧𝐝 𝐑𝐞𝐠𝐞𝐧𝐞𝐫𝐚𝐭𝐢𝐯𝐞 𝐌𝐞𝐝𝐢𝐜𝐢𝐧𝐞: 𝐀 𝐏𝐫𝐨-𝐀𝐠𝐢𝐧𝐠 𝐏𝐞𝐫𝐬𝐩𝐞𝐜𝐭𝐢𝐯𝐞 𝐨𝐧 𝐁𝐨𝐝𝐲 𝐑𝐞𝐣𝐮𝐯𝐞𝐧𝐚𝐭𝐢𝐨𝐧
I discuss the rapid rise of peptides and regenerative medicine and their growing role in body rejuvenation and longevity-focused care. I break down commonly discussed treatments derived from various biological sources, including exosomes and other bioactive compounds, and how they are marketed to stimulate the body’s natural repair and regeneration processes.
I also address the current limitations, potential risks, and regulatory concerns surrounding these therapies, including the lack of FDA approval for certain injectable treatments, emphasizing the importance of evidence-based medicine and responsible adoption of emerging technologies.
🎧 Listen to the full episode of The Pro-Aging Podcast to hear the complete conversation and my perspective on navigating regenerative medicine thoughtfully, safely, and with long-term outcomes in mind.
𝐓𝐡𝐞 𝐏𝐫𝐞𝐦𝐚𝐭𝐮𝐫𝐞 𝐏𝐫𝐨𝐦𝐢𝐬𝐞 𝐨𝐟 𝐅𝐚𝐜𝐢𝐚𝐥 𝐏𝐥𝐚𝐬𝐭𝐢𝐜 𝐒𝐮𝐫𝐠𝐞𝐫𝐲: 𝐀 𝐏𝐫𝐨-𝐀𝐠𝐢𝐧𝐠 𝐃𝐞𝐫𝐦𝐚𝐭𝐨𝐥𝐨𝐠𝐢𝐬𝐭’𝐬 𝐏𝐞𝐫𝐬𝐩𝐞𝐜𝐭𝐢𝐯𝐞
In this episode, I discuss the growing trend of over-marketing facial plastic surgery to younger patients and the misconceptions surrounding so-called preventative procedures. I explain why surgical intervention in the early 40s can sometimes lead to suboptimal outcomes, including the need for unnecessary repeat surgeries over time.
I also break down the importance of skin health, collagen preservation, and non-surgical strategies as a first-line approach, emphasizing pro-aging, thoughtful care rather than rushing into invasive procedures before they are truly indicated.
🎧 Listen to the full S3E10 of The Pro-Aging Podcast to hear the complete episode, where I break down the biggest shifts in aesthetics in 2025 and share what I believe is coming next in 2026.
𝐓𝐡𝐞 𝐏𝐫𝐨-𝐀𝐠𝐢𝐧𝐠 𝐏𝐨𝐝𝐜𝐚𝐬𝐭: 𝟐𝟎𝟐𝟓 𝐘𝐞𝐚𝐫 𝐢𝐧 𝐑𝐞𝐯𝐢𝐞𝐰
We’re wrapping up the season with a special solo episode.
In this final episode, I break down the biggest shifts in aesthetic medicine in 2025 and what I believe is coming next in 2026, from injectable awakenings to surgical hype and the rise of regenerative medicine.
𝐖𝐞 𝐝𝐢𝐯𝐞 𝐢𝐧𝐭𝐨 𝐭𝐡𝐞 𝐦𝐨𝐬𝐭 𝐭𝐚𝐥𝐤𝐞𝐝-𝐚𝐛𝐨𝐮𝐭 𝐝𝐞𝐯𝐞𝐥𝐨𝐩𝐦𝐞𝐧𝐭𝐬 𝐨𝐟 𝐭𝐡𝐞 𝐲𝐞𝐚𝐫, 𝐢𝐧𝐜𝐥𝐮𝐝𝐢𝐧𝐠:
✨ The rise of “filler fear” and why injectables still have a place when used responsibly
✨ The year of celebrity surgery and the deep plane facelift hype, plus why technique and timing matter
✨ Regenerative medicine and peptides, what’s promising, what’s over-marketed, and what needs more data
✨ Why the next 5 to 10 years will be the decade of maintenance, with lasers, resurfacing, and injectable-sparing technologies
✨ Why fat is poised to be the next major focus, and the resurgence of microfat and nanofat for regenerative results
To close, I share what I’m watching for 2026 and beyond as aesthetics continues moving toward smarter, safer, more natural pro-aging outcomes.
Thank you for listening all year. Your support is what makes this podcast possible. Here’s to a strong finish to 2025 and an even better 2026. 🥂
🎧 Click the link in bio to listen to the full episode and catch up on the rest of the season wherever you get your podcasts.
For more on pro-aging, check out my book, The Pro-Aging Playbook.
𝐆𝐞𝐧𝐭𝐥𝐞, 𝐄𝐟𝐟𝐞𝐜𝐭𝐢𝐯𝐞 𝐋𝐄𝐃 𝐂𝐚𝐫𝐞 𝐟𝐨𝐫 𝐀𝐥𝐥 𝐒𝐤𝐢𝐧 𝐓𝐲𝐩𝐞𝐬
Annie, our Director of Operations and Creative Director at PFRANKMD, shares one of the ways our team supports skin health between in-office treatments.
This professional-grade at-home LED mask was selected by our providers with sensitive skin in mind and designed to deliver consistent, clinically studied light therapy without irritation or downtime. With multiple customizable light settings, it helps target concerns like breakouts, pigmentation, uneven texture, and early signs of aging.
Red, blue, and near-infrared wavelengths work together to support collagen production, calm inflammation, improve clarity, and enhance overall radiance. The flexible silicone design contours comfortably to the face, ensuring even light coverage in just 10 minutes per session.
Safe, gentle, and suitable for all skin types, the Lumiera PFRANKMD LED Mask brings spa-quality technology into your daily routine, supporting long-term skin health as part of a comprehensive, pro-aging approach to care.
Tap the link in our bio learn more or ask our team if this at-home LED treatment is right for you.
𝐌𝐢𝐜𝐫𝐨𝐋𝐢𝐩𝐨 𝐭𝐨 𝐭𝐡𝐞 𝐀𝐫𝐦𝐬
MicroLipo is about precision. It allows us to selectively remove stubborn fat while preserving natural contours and proportions of the arm.
In these cases, the results are not about aggressive fat removal or chasing an overly thin look. The goal is balance and refinement.
By combining MicroLipo with surgical microneedling, we are able to address both shape and skin quality. Fat is carefully sculpted, while microneedling stimulates collagen to improve texture, firmness, and overall smoothness.
The outcome is arms that look more defined, smoother, and naturally proportionate to the body.
To learn if MicroLipo to the arms is right for you, schedule a consultation at the link in bio.
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐂𝐎𝟐 𝐋𝐚𝐬𝐞𝐫 𝐯𝐬 𝐌𝐢𝐫𝐢𝐚: 𝐔𝐧𝐝𝐞𝐫𝐬𝐭𝐚𝐧𝐝𝐢𝐧𝐠 𝐀𝐜𝐧𝐞 𝐒𝐜𝐚𝐫 𝐎𝐩𝐭𝐢𝐨𝐧𝐬
@dr.connieyang breaks down two of our most effective options for acne scarring. The CO2 laser is the gold standard for deeper collagen remodeling and more dramatic textural improvement, though it comes with a longer recovery. Miria is a novel non-ablative laser that offers controlled resurfacing with less aggressiveness and shorter downtime.
Both options can be transformative when used thoughtfully and in expert hands. At PFRANKMD, our goal is always to match the right device to the right patient for the safest, most effective pro-aging outcome.
𝐓𝐚𝐩 𝐭𝐡𝐞 𝐥𝐢𝐧𝐤 𝐢𝐧 𝐛𝐢𝐨 𝐨𝐫 𝐜𝐚𝐥𝐥 (212) 327-2919 to schedule a consultation.
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐂𝐎𝟐 𝐋𝐚𝐬𝐞𝐫 𝐟𝐨𝐫 𝐅𝐢𝐧𝐞 𝐋𝐢𝐧𝐞𝐬 𝐚𝐧𝐝 𝐖𝐫𝐢𝐧𝐤𝐥𝐞𝐬 𝐀𝐫𝐨𝐮𝐧𝐝 𝐭𝐡𝐞 𝐌𝐨𝐮𝐭𝐡
The mouth is one of the first areas to show visible aging. Years of sun exposure, collagen loss, and constant muscle movement make this region especially prone to fine lines and deeper etched-in wrinkles that topicals cannot correct. This is where advanced CO2 resurfacing remains the gold standard of lasers for true skin rejuvenation.
CO2 can treat the delicate crepey skin around the mouth that even a facelift cannot improve. It works by tightening, smoothing, and rebuilding the skin from the inside out through powerful collagen and elastin stimulation. Even one treatment can dramatically refine texture, soften wrinkles, and restore a firmer, more youthful appearance.
At PFRANKMD, we use precision-based energy settings to resurface the area safely and effectively with measurable, long-term results. Skin continues to improve for months as new collagen forms.
Click the link in bio or call (212) 327-2919 to schedule a consultation and elevate your long-term skin health.
𝐔𝐥𝐭𝐡𝐞𝐫𝐚𝐩𝐲 𝐏𝐫𝐢𝐦𝐞 𝐟𝐨𝐫 𝐋𝐨𝐰𝐞𝐫 𝐅𝐚𝐜𝐞 𝐚𝐧𝐝 𝐉𝐨𝐰𝐥 𝐓𝐢𝐠𝐡𝐭𝐞𝐧𝐢𝐧𝐠
This patient presented with concerns about early laxity along the lower face and jowl area. Ultherapy Prime was used to deliver precise, targeted tightening to the deeper structural layers that define the lower face. The results shown here are four months after treatment, during the peak window of collagen remodeling.
Ultherapy works by delivering micro-focused ultrasound energy to the foundational tissues that support lift and contour. This stimulates new collagen, creating gradual tightening and improved definition. Patients often begin noticing changes around the four-week mark, with full results developing between three and six months.
Ultherapy is an excellent option for patients looking for visible lift, enhanced jawline contour, and tightening without surgery or downtime.
Treatment performed by Registered Nurse Jennifer Schroder @bomb.ass.skin
𝐒𝐭𝐫𝐞𝐭𝐜𝐡 𝐌𝐚𝐫𝐤 𝐓𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭: 𝐑𝐞𝐝𝐧𝐞𝐬𝐬 𝐚𝐧𝐝 𝐒𝐤𝐢𝐧 𝐐𝐮𝐚𝐥𝐢𝐭𝐲
Stretch marks form when skin’s elastic fibers are stretched beyond their capacity to repair, often from pregnancy, growth spurts, weight changes, or hormonal shifts.
This patient began treatment while her stretch marks were still red, which is the most responsive stage for improvement. In the photos, you can see a clear reduction in redness, a smoother texture across the abdomen, and softer edges where the stretch marks once appeared deeper and more inflamed.
Treatment began with Vbeam to calm the redness and vascular activity. Pico was then added to break up pigment and stimulate collagen remodeling. Customized topicals between sessions supported ongoing healing and improved overall skin quality.
Her texture, color, and uniformity have improved significantly. Most patients require 6 to 10 treatments for visible fading, depending on the age, depth, and type of stretch marks. If you prolong treatment, the stretch marks will most likely be permanent and significantly harder to treat.
Every body is different, which is why PFRANKMD uses advanced, customized treatment plans to achieve the best possible outcome.
✨ Treatment performed by Registered Nurse Jennifer Schroder @bomb.ass.skin
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Aesthetic and Longevity Healthcare
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PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐌𝐢𝐫𝐢𝐚: 𝐀𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐍𝐨𝐧 𝐀𝐛𝐥𝐚𝐭𝐢𝐯𝐞 𝐒𝐤𝐢𝐧 𝐑𝐞𝐣𝐮𝐯𝐞𝐧𝐚𝐭𝐢𝐨𝐧
Miria is a non invasive treatment that reduces fine lines, softens wrinkles, improves crepey skin, and enhances overall texture with minimal downtime. The device delivers cone shaped heat deep into the dermis to stimulate collagen, tighten skin, and support long term maintenance for patients who want smoother, firmer, more youthful looking skin without the recovery of ablative lasers.
Watch the video to see how this technology penetrates deeply, creates controlled heat, and rejuvenates the skin while keeping recovery minimal and treatment tolerable.
Click the link in bio to learn if this treatment is right for you.
𝐈𝐧 𝐂𝐚𝐬𝐞 𝐘𝐨𝐮 𝐌𝐢𝐬𝐬𝐞𝐝 𝐓𝐡𝐞 𝐃𝐞𝐫𝐦 𝐂𝐨𝐮𝐜𝐡: 𝐓𝐡𝐞 𝐀𝐫𝐭 𝐨𝐟 𝐑𝐞𝐜𝐨𝐯𝐞𝐫𝐲
On this derm couch, we dive into the art of post-treatment healing—keeping it simple from skin to surgery. From minimal skincare and internal wellness to the benefits of peptides, we explore why less really is more when it comes to recovery.
Watch for more insights on how to support your body and skin from the inside out for optimal healing and lasting results.
𝐀𝐜𝐡𝐢𝐞𝐯𝐞 𝐓𝐢𝐠𝐡𝐭𝐞𝐫, 𝐒𝐦𝐨𝐨𝐭𝐡𝐞𝐫 𝐒𝐤𝐢𝐧 𝐰𝐢𝐭𝐡 𝐌𝐢𝐫𝐢𝐚 𝐒𝐤𝐢𝐧 𝐓𝐢𝐠𝐡𝐭𝐞𝐧𝐢𝐧𝐠
Miria Skin Tightening is designed to target superficial skin concerns, enhancing elasticity, reducing fine lines, and improving the appearance of acne scars for a refreshed, youthful look.
This advanced treatment uses innovative energy-based technology to stimulate collagen production, delivering natural, long-lasting results with minimal downtime.
Whether you’re looking to firm the face, neck, or body, or improve skin texture and acne scars, Miria offers a customized solution tailored to your skin’s unique needs. Say goodbye to superficial skin concerns and hello to rejuvenation!
✨Call (212) 327-2919 or click the link in bio to schedule your consultation.
Frequently Asked Questions: Peptide Therapy at PFRANKMD
What are peptides and how do they work?
Peptides are small chains of amino acids that act as messengers in the body, instructing cells to carry out specific functions like healing, repair, or hormone release.
Are peptides safe?
Yes. When prescribed and administered under medical supervision using pharmacy-grade sources, peptides are generally well-tolerated and have low risk of adverse effects.
How long does it take to see results from peptide therapy?
Most patients begin noticing changes within a few weeks. Full benefits are typically experienced after 8–12 weeks of consistent use.
Can peptides help with weight loss?
Yes. Certain peptides such as CJC-1295, Tesamorelin, and GLP-1 analogs can support fat loss, improve metabolism, and regulate appetite.
Do I need lab work before starting peptide therapy?
Yes. A full health evaluation, including lab testing, helps ensure your treatment plan is safe, targeted, and effective.
Is peptide therapy only for older adults?
No. Peptide therapy can benefit adults of any age who are seeking to enhance their wellness, athletic performance, skin health, or recovery.
How is peptide therapy different at PFRANKMD?
Our approach is precision-based, backed by the latest longevity research, and delivered under the guidance of leading medical experts in the field of aesthetic and functional wellness.