Niagen IV Therapy

Advanced NAD+ support through precision IV infusion

Targeted Cellular Replenishment

Niagen IV delivers pharmaceutical-grade nicotinamide riboside chloride (NRCl), a clinically studied NAD+ precursor that supports cellular metabolism, energy production, and healthy aging. As part of our integrated aesthetic and longevity healthcare offerings, this therapy helps optimize your internal health to match your external goals.

Why Niagen IV at PFRANKMD

Rapid NAD+ replenishment—20% increase within 3 hours Efficient intracellular delivery with reduced GI or immune side effects Shorter infusion time—typically 10 minutes to 3 hours Pharmaceutical-grade sourcing under FDA-compliant standards Part of a personalized longevity and optimization protocol

How It Works

Unlike traditional NAD+ infusions, which require long infusion times and often cause uncomfortable side effects, Niagen IV uses nicotinamide riboside chloride to bypass rate-limiting steps in NAD+ metabolism. Once infused, NRCl is efficiently absorbed and converted into NAD+ within cells, enhancing mitochondrial function and supporting systemic cellular health.

Niagen (NR) IV Drips

What is Niagen® (NR) IV Drip Therapy?

Experience the superior way to feel the effects of NAD+ therapy to help reduce age- and stress-related cellular damage and improve energy and metabolism.

Benefits of Niagen (NR) IV Drips may include:

– Improved cellular and metabolic health

– Enhanced cellular energy to combat fatigue

– Reduced oxidative stress for faster recovery

– Decreased inflammation for healthier aging

– Boosted cognitive function

The Niagen (NR) IV Drips Experience

Why is NR superior to NAD+?

When receiving NAD+ therapy, the active form of NAD+ is injected directly into your bloodstream. However, high concentrations of NAD+ are not naturally present in the body, so this may cause adverse experiences, such as headaches and nausea. Since NR is the precursor to NAD+ that is converted naturally inside cells, Niagen (NR) has been shown to provide 20% higher levels of NAD+ at the 3-hour mark compared to baseline with fewer adverse experiences.

For this medical service, please plan to arrive early to complete any necessary paperwork and participate in a Telemedicine consultation with a Nurse Practitioner. Medical paperwork needs to be completed once a year. During your Telemedicine session, you’ll have the opportunity to discuss your health history, wellness goals and any questions you may have about the treatment. A Registered Nurse will then take your vital signs before guiding you to a comfortable space for your infusion and carefully insert a small catheter into your vein. We encourage you to relax during the treatment by enjoying a book, listening to a podcast or working on your laptop.

The Niagen IV Drip Therapy experience does not require a loading dose and offers a 75% faster infusion time, compared to NAD+ IV Drip Therapy.

After the Niagen (NR) IV Drip is completed, you can enjoy a refreshing cleansing IV infusion. This drip includes essential B Vitamins and amino acids like Glutamine and Proline to support the creation of new cells, boost recovery and enhance immunity and digestion.

NR research is continually evolving, and we may adjust our options and protocols accordingly.

What to Expect

Consultation: Your provider will evaluate your overall health, goals, and baseline labs to determine if Niagen IV fits into your personal optimization protocol.

Infusion: The IV drip typically lasts about 45 minutes, depending on dose and tolerance.

Aftercare: Most patients report a subtle but steady improvement in focus, energy, and recovery within 24–72 hours.

Frequently Asked Questions

What is Niagen IV?

Niagen IV is an intravenous therapy that delivers nicotinamide riboside chloride (NRCl), a clinically tested NAD+ precursor that helps restore intracellular NAD+ levels, supporting cellular repair, energy production, and overall vitality.

How is this different from NAD+ IV therapy?

Niagen IV uses a precursor molecule (NRCl) rather than NAD+ itself, allowing for faster absorption, improved intracellular uptake, and fewer side effects such as nausea or headaches.

How often should I receive Niagen IV?

Frequency is based on your health goals, lifestyle, and lab results. Some incorporate it monthly for longevity maintenance, while others may benefit from more frequent sessions as part of a targeted program.

Is Niagen IV safe?

Yes. It is produced under strict quality standards in compliance with FDA regulations. In clinical trials, Niagen IV was well-tolerated with no serious adverse events.

Can it be combined with other treatments?

Absolutely. Niagen IV is often combined with skin rejuvenation, hormonal optimization, and metabolic support as part of a whole-body wellness strategy at PFRANKMD.

Ready to Optimize from the Inside Out?

Schedule your Niagen IV consultation to explore how targeted NAD+ replenishment can support your performance, vitality, and longevity.
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