Niagen IV Therapy

Advanced NAD+ support through precision IV infusion

Targeted Cellular Replenishment

Niagen IV delivers pharmaceutical-grade nicotinamide riboside chloride (NRCl), a clinically studied NAD+ precursor that supports cellular metabolism, energy production, and healthy aging. As part of our integrated aesthetic and longevity healthcare offerings, this therapy helps optimize your internal health to match your external goals.

Why Niagen IV at PFRANKMD

  • Rapid NAD+ replenishment—20% increase within 3 hours

  • Efficient intracellular delivery with reduced GI or immune side effects

  • Shorter infusion time—typically 10 minutes to 3 hours

  • Pharmaceutical-grade sourcing under FDA-compliant standards

  • Part of a personalized longevity and optimization protocol

How It Works

Unlike traditional NAD+ infusions, which require long infusion times and often cause uncomfortable side effects, Niagen IV uses nicotinamide riboside chloride to bypass rate-limiting steps in NAD+ metabolism. Once infused, NRCl is efficiently absorbed and converted into NAD+ within cells, enhancing mitochondrial function and supporting systemic cellular health.

Niagen (NR) IV Drips

What is Niagen® (NR) IV Drip Therapy?

Experience the superior way to feel the effects of NAD+ therapy to help reduce age- and stress-related cellular damage and improve energy and metabolism.

Benefits of Niagen (NR) IV Drips may include:

– Improved cellular and metabolic health

– Enhanced cellular energy to combat fatigue

– Reduced oxidative stress for faster recovery

– Decreased inflammation for healthier aging

– Boosted cognitive function

The Niagen (NR) IV Drips Experience

Why is NR superior to NAD+?

When receiving NAD+ therapy, the active form of NAD+ is injected directly into your bloodstream. However, high concentrations of NAD+ are not naturally present in the body, so this may cause adverse experiences, such as headaches and nausea. Since NR is the precursor to NAD+ that is converted naturally inside cells, Niagen (NR) has been shown to provide 20% higher levels of NAD+ at the 3-hour mark compared to baseline with fewer adverse experiences.

For this medical service, please plan to arrive early to complete any necessary paperwork and participate in a Telemedicine consultation with a Nurse Practitioner. Medical paperwork needs to be completed once a year. During your Telemedicine session, you’ll have the opportunity to discuss your health history, wellness goals and any questions you may have about the treatment. A Registered Nurse will then take your vital signs before guiding you to a comfortable space for your infusion and carefully insert a small catheter into your vein. We encourage you to relax during the treatment by enjoying a book, listening to a podcast or working on your laptop.

The Niagen IV Drip Therapy experience does not require a loading dose and offers a 75% faster infusion time, compared to NAD+ IV Drip Therapy.

After the Niagen (NR) IV Drip is completed, you can enjoy a refreshing cleansing IV infusion. This drip includes essential B Vitamins and amino acids like Glutamine and Proline to support the creation of new cells, boost recovery and enhance immunity and digestion.

NR research is continually evolving, and we may adjust our options and protocols accordingly.

What to Expect

Consultation: Your provider will evaluate your overall health, goals, and baseline labs to determine if Niagen IV fits into your personal optimization protocol.

Infusion: The IV drip typically lasts about 45 minutes, depending on dose and tolerance.

Aftercare: Most patients report a subtle but steady improvement in focus, energy, and recovery within 24–72 hours.

Schedule your Niagen IV consultation to explore how targeted NAD+ replenishment can support your performance, vitality, and longevity.

Frequently Asked Questions

What is Niagen IV?

Niagen IV is an intravenous therapy that delivers nicotinamide riboside chloride (NRCl), a clinically tested NAD+ precursor that helps restore intracellular NAD+ levels, supporting cellular repair, energy production, and overall vitality.

How is this different from NAD+ IV therapy?

Niagen IV uses a precursor molecule (NRCl) rather than NAD+ itself, allowing for faster absorption, improved intracellular uptake, and fewer side effects such as nausea or headaches.

How often should I receive Niagen IV?

Frequency is based on your health goals, lifestyle, and lab results. Some incorporate it monthly for longevity maintenance, while others may benefit from more frequent sessions as part of a targeted program.

Is Niagen IV safe?

Yes. It is produced under strict quality standards in compliance with FDA regulations. In clinical trials, Niagen IV was well-tolerated with no serious adverse events.

Can it be combined with other treatments?

Absolutely. Niagen IV is often combined with skin rejuvenation, hormonal optimization, and metabolic support as part of a whole-body wellness strategy at PFRANKMD.

SOCIAL MEDIA
𝐁𝐨𝐨𝐬𝐭 𝐘𝐨𝐮𝐫 𝐄𝐧𝐞𝐫𝐠𝐲 𝐚𝐧𝐝 𝐋𝐨𝐧𝐠𝐞𝐯𝐢𝐭𝐲 𝐰𝐢𝐭𝐡 𝐚 𝐍𝐢𝐚𝐠𝐞𝐧 𝐃𝐫𝐢𝐩 𝐚𝐭 𝐏𝐅𝐑𝐀𝐍𝐊𝐌𝐃

As we move through the final stretch of summer, Dr. Frank is prioritizing recovery, energy, and cellular health with the Niagen drip—an advanced IV therapy designed to efficiently deliver NADH, a key coenzyme involved in cellular energy metabolism and healthy aging.

NADH (Nicotinamide Adenine Dinucleotide + Hydrogen) helps your body create ATP—the fuel that powers every cell. But NAD levels naturally decline with age, stress, and environmental exposure (like summer sun and travel), often resulting in fatigue, brain fog, and slower recovery.

The Niagen drip is a next-gen solution that works faster and more comfortably than traditional NAD infusions. It boosts cellular NADH levels by 20% in just three hours—helping patients improve energy, sleep, cognitive clarity, and recovery without the downtime.

It’s also easy to stack with other treatments at PFRANKMD, making it a smart, time-efficient part of your aesthetic and longevity plan.

At PFRANKMD, we believe in optimizing from the inside out—so you can look and feel your best, not just this summer, but year-round.
•
Aesthetic and Longevity Healthcare
•
PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐀𝐜𝐡𝐢𝐞𝐯𝐢𝐧𝐠 𝐭𝐡𝐞 𝐀𝐢𝐫𝐛𝐫𝐮𝐬𝐡𝐞𝐝, 𝐅𝐢𝐥𝐭𝐞𝐫𝐞𝐝 𝐋𝐨𝐨𝐤 𝐰𝐢𝐭𝐡 𝐂𝐎𝟐 𝐋𝐚𝐬𝐞𝐫 𝐑𝐞𝐬𝐮𝐫𝐟𝐚𝐜𝐢𝐧𝐠

CO2 laser resurfacing, a procedure that can get rid of fine lines, even out pigmentation, shrink pores, and tighten skin in a way that face surgery can’t. It has a one-week downtime, is painless, and done in a 15-minute procedure under IV sedation. This classic but ever-evolving technology can make fine lines, smoker’s eyes, and crepey skin under the eyes disappear, giving you the ‘shrink-wrapped’ look you can only get from filters.

CO2 Laser with the Fraxel Re:pair requires the expertise of skilled practitioners who create a customized treatment plan catered to each individual’s unique skin concerns. 

Call (212) 327-2919 or click the link in bio to schedule a consultation.
•
Aesthetic and Longevity Healthcare
•
PFRANKMD|The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
•
WARNING: This treatment utilizes an FDA-approved medical device that requires informed consent and discussion of its risks and benefits with a licensed healthcare professional. Like all medical procedures, only doctors, nurses and Physician Assistants (PAs) can legally recommend, give consent, perform, or even attach such devices to patients. In most states, especially NY, Aestheticians of any licensure CANNOT ethically or legally apply or perform medical device treatments. At PFRANKMD by Dr. Paul Jarrod Frank, only licensed healthcare professionals to perform such procedures. For state laws, go to www.americanmedspa.org. To report misconduct, go to www.dos.ny.gov/licensing/1507-f.pdf
𝐈𝐕 𝐕𝐒𝐄𝐋 𝐒𝐭𝐞𝐦 𝐂𝐞𝐥𝐥 𝐈𝐧𝐟𝐮𝐬𝐢𝐨𝐧:

We are excited to introduce the latest treatment, the VSEL Stem Cell IV infusion. Watch along as I get an IV infusion filled with my own powerful stem cells to address joint pains, inflammation, and overall well-being utilizing a laser-guided activation protocol. As we embrace a pro-aging lifestyle, it’s not just about what we do on the outside but also about working from the inside and nurturing our bodies from within. 

At PFRANKMD, we are at the forefront of regenerative medicine, leveraging cutting-edge VSEL technology to ensure we provide the most advanced treatments possible. We look forward to sharing more about these treatments 

Click the link in the bio and call (212) 327-2919 to schedule a consultation to learn more.
•
Bespoke Aesthetic Healthcare
•
PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
𝐔𝐧𝐥𝐨𝐜𝐤𝐢𝐧𝐠 𝐭𝐡𝐞 𝐏𝐨𝐰𝐞𝐫 𝐨𝐟 𝐕𝐒𝐄𝐋𝐬: The Cutting-Edge Approach to Pro-Aging 

Did you know working from the inside out is just as crucial in our pro-aging journey? 

That’s why PFRANKMD is diving into the world of regenerative medicine and harnessing VSELs (tiny embryonic-like stem cells) for optimal health and longevity. 

Stem cells can turn into various cells throughout the human body. These little cells, found in our tissue and blood, are present dormant since birth and activated in stressful situations such as a heart attack. They are essentially  “backup” stem cells for repair.

This is PRP 2.0! With direct injection into desired skin sites and IV infusions activate by external laser therapy, we can send VSEL stem cells directly to their preferred targets of inflammation and symptoms of aging. 

These combined working techniques from the inside and out exemplify all PFRANKMD Pro-Aging therapies, providing remarkable advances for cosmetic concerns only available at PFRANKMD.

Click the link in bio ⬆️ for additional information and call (212) 327-2919 to schedule a consultation.

Bespoke Aesthetic Healthcare
•
PFRANKMD| The Most Cutting-Edge Technologies| Customized Signature Treatments| Only Licensed Healthcare Professionals
Secret Link