Mental Health and Wellness
Optimizing Your Mind for Total Longevity Care
What Is ExoMind?
Next-Generation Support for Cognitive Health and Resilience
ExoMind is a proprietary regenerative treatment designed to support the nervous system and cognitive function by delivering high-density extracellular vesicles and neurotrophic factors directly to the body. These vesicles play a vital role in cellular communication, supporting brain plasticity, mood regulation, and overall mental clarity.
Whether you’re experiencing hormonal fluctuations from menopause, cognitive changes due to stress or aging, or mental fog while on GLP-1 medications, ExoMind enhances your capacity to think clearly, recover faster, and regain emotional balance—without relying on prescription medications.

Why We Test Your Blood for Mental Health
Understanding What’s Happening Inside
We use comprehensive blood testing to identify biological drivers of mental disruption that are often overlooked, including:
– Hormonal imbalances (estrogen, progesterone, testosterone, cortisol, thyroid)
– Nutritional deficiencies (B12, Vitamin D, magnesium, iron)
– Markers of inflammation and oxidative stress
– Metabolic and adrenal function
This clinical insight allows us to personalize a plan that supports both your mental and physical health—one that might include supplementation, bioidentical hormone replacement, IV therapy, or regenerative treatments like ExoMind.
Menopause, Hormones & Mood
Reframing the Conversation Around Hormonal Change
The perimenopausal and menopausal transition is often accompanied by anxiety, insomnia, irritability, and depression—all of which stem from significant hormonal fluctuations. These changes aren’t just “part of getting older.” They’re signals from your body that need to be understood and addressed.
With targeted labs and customized longevity care, we help you regain control over your mind and body—so you can feel more like yourself again.
Mental Health on GLP-1s
Addressing the Hidden Side Effects of Rapid Weight Loss
GLP-1 medications can be highly effective for weight management, but many patients experience unintended consequences like muscle loss, low energy, and mood shifts. At PFRANKMD, we support patients on GLP-1s with muscle-preserving strategies, metabolic labs, and mental wellness treatments that ensure weight loss doesn’t come at the cost of mental clarity or vitality.
Why Mental Wellness Is Essential in Aesthetic & Longevity Medicine
Frequently Asked Questions (FAQ)
ExoMind uses a purified matrix of extracellular vesicles and neurotrophic factors derived from human placental tissue. It is administered either through injection or IV, depending on the patient’s treatment plan and goals.
Symptoms such as anxiety, irritability, poor concentration, mood swings, and disrupted sleep often indicate hormonal imbalance. A detailed blood panel will identify if hormones like estrogen, testosterone, cortisol, or thyroid hormones are playing a role.
Absolutely. ExoMind and hormone optimization are appropriate for anyone seeking to improve cognitive clarity, emotional balance, and performance under stress—whether or not you're taking weight loss or other medications.
We typically recommend a baseline panel followed by re-testing every 3–6 months, depending on your health goals and treatment plan.
No. Our approach is integrative. We support the biological and regenerative side of mental health, which can complement traditional therapies. We work with you and your broader care team when needed.
Ready to feel clearer, stronger, and more connected to your goals?
Call (212) 327-2919 or click the button below to book your consultation
to begin your personalized mental health and longevity plan at PFRANKMD.